|
|
|
|
|
|
| NIH |
Alabama-Zambia HIV Vaccine Clinical Trials Unit |
HIV/AIDS |
Drug Development |
|
| |
(Principal Investigator: Mark Mulligan. 2000-2005.) This grant supports establishment of an HIV Vaccine Trials Unit (HVTU) with a main site at the...
|
| NIH |
HIV Vaccine Trial Site Development for Zambia |
HIV/AIDS |
Drug Development |
|
| |
(PI: Rosemary Musonda. 2002-2004.) A grant to establish a vaccine trial site in Ndola, Zambia. Specific objectives include identifying cohorts of...
|
| NIH |
Planning Randomized Controlled Trials Antiretroviral |
HIV/AIDS |
Drug Development |
|
| |
(PI: Isaac Zulu. 2001-2003.) This grant is facilitating preparations for trials of antiretroviral and prophylactic therapies in Zambia.
|
| NIH |
Acyclovir to Prevent HIV Acquisition in HSV-2 Positive Persons |
HIV/AIDS |
Drug Development |
|
| |
(PI: Connie Celum. 2002-2005.) Herpes Simplex Type 2 (HSV-2) has been shown in studies conducted in Uganda to increase susceptibility to HIV by a...
|
| NIH |
UAB AIEDRP: Immune Control and Escape in Acute Infection |
HIV/AIDS |
Drug Development |
|
| |
(PI: J.M. Kilby. 1997-2007.) An assessment of virologic and immunologic changes at the molecular level in patients treated with highly active...
|
| NIH |
Disseminated Tuberculosis in HIV Infection |
HIV/AIDS,Tuberculosis |
Drug Development |
|
| |
(PI: C.F. von Reyn. 2000-2005.) Professor von Reyn of Dartmouth College is testing a mycobacterium vaccine for its efficacy in reducing...
|
| NIH |
HIV, TB and Malaria Vaccine Development for Africa |
HIV/AIDS,Tuberculosis,Malaria |
Drug Development |
|
| |
(PI: Barton Haynes. 2003-2008.) Professor Haynes of Duke University is working on a trivalent vaccine that will use an attenuated mycobacterium...
|
| NIH |
Child Sexual Abuse in Zambia: Epidemiology and Prevention |
HIV/AIDS |
Epidemiology |
Prevention |
| |
(PI: Susan Allen. 2003-2006.) The topic of child sexual abuse has not been closely studied in Zambia, but it is known to contribute to the spread of...
|
| NIH |
Clinical and Mucosal Interactions Between HSV and HIV |
HIV/AIDS |
Epidemiology |
|
| |
(PI: Lawrence Corey. 2003-2008.) The Zambian component of this multi-part, international study investigates the hypothesis that "HSV-2 infection of...
|
| NIH |
Role of V1V2 in HIV Transmission and Pathogenesis |
HIV/AIDS |
Epidemiology |
|
| |
(PI: Cynthia Derdeyn. 2004-2008.) This is a study of the role the V1V2 hypervariable regions on the surface of the HIV-1 core in the transmission of...
|
| NIH |
HIV-1 p24 based viral load assay in breast milk & serum |
HIV/AIDS |
Epidemiology |
|
| |
(PI: Andrzej Drukier. 1999-2003.) This study examines the relationship between viral load in breast milk and HIV transmission.
|
| NIH |
Evolution of Clade C HIV-1 in Infected Children |
HIV/AIDS |
Epidemiology |
|
| |
(PI: Charles Wood. 2001-2006.) A study to longitudinally isolate and characterize Clade C viruses from Zambian infants perinatally infected by HIV-1.
|
| NIH |
International Studies of Acquired Immune Deficiency Syndrome |
HIV/AIDS |
Epidemiology |
|
| |
(PI: Thomas Quinn. FY 2003) A large study of HIV transmission including cohorts from Uganda, Congo, Zambia, Zimbabwe, South Africa, India, China and...
|
| NIH |
Core -- Virus Isolation Facility |
HIV/AIDS |
Epidemiology |
Prevention |
| |
(PI: Charles Wood. 2002-2005.) An HIV virus isolation study carried out with mother/infant pairs at the University Teaching Hospital in Lusaka. The...
|
| NIH |
Virologic Correlates of Heterosexual Transmission |
HIV/AIDS |
Epidemiology |
|
| |
(PI: Eric Hunter. 2002-2007.) An analysis of variable regions of gp120 in HIV to determine what variants have a selective advantage for heterosexual...
|
| NIH |
DNA Methylation as an Epigenetic Host Factor in HIV/AIDS |
HIV/AIDS |
Epidemiology |
|
| |
(PI: Jianming Tang. 2003-2007.) A genetic study of HIV specimens obtained through the Zambia-University of Alabama HIV Research Project.
|
| NIH |
Assessment of MTCT Prevention programs on antenatal care |
HIV/AIDS |
Epidemiology |
|
| |
(P.I.:POTTER, DARA G. 2004-2005)This study will assess the impact of programs of mother-to-child HIV transmission prevention on non-HIV specific...
|
| NIH |
Severe Malarial Anemia and Altered Immune Function |
Malaria |
Epidemiology |
|
| |
(PI: Victor Gordeuk. 2000-2005.) This study is investigating Th-1 and Th-2 immune responses to malaria in children.
|
| NIH |
Assessment of MTCT Prevention Programs on Antenatal Care |
HIV/AIDS |
Prevention |
|
| |
(PI: Dara Potter. 2004?) This University of Alabama-affiliated study is investigating the ancillary health benefits, if any, for pregnant women in...
|
| NIH |
Couples HIV Counseling and Testing in Two African Capitals |
HIV/AIDS |
Prevention |
|
| |
(PI: Susan Allen. 2002-2007.) A research team based at the University of Alabama is implementing this voluntary counseling and testing program for...
|
| NIH |
Zambia/US Research Partnership in HIV Prevention |
HIV/AIDS |
Prevention |
|
| |
(PI: Deborah Jones. 2002-2007.) A collaboration between Barry University in the US and the University of Zambia and the University Teaching Hospital...
|
| NIH |
UAB-Zambia-Haiti HIV Prevention Trials Unit |
HIV/AIDS |
Prevention |
|
| |
(PI: Sten Vermund. 2000-2004.) Research foci in Zambia include HIV prevention in discordant couples and pediatric vaccine trials.
|
| NIH |
Family Planning Promotion in HIV-Infected Zambians |
HIV/AIDS |
Prevention |
|
| |
(PI: Susan Allen. 2001-2006.) This study is aimed at reducing pregnancies among HIV positive persons.
|
| NIH |
Career Development Award in International Women's Health |
HIV/AIDS |
Prevention |
|
| |
(PI: Elizabeth Stringer. 2001-2004.) Award recipient is conducting a randomized clinical trial of the intrauterine contraceptive device (IUD) versus...
|
| NIH |
Barrier Acceptability in Culturally Diverse HIV+ Women |
HIV/AIDS |
Prevention |
|
| |
(PI: Stephen Weiss. 2000-2005.) This study includes a cohort of 450 HIV+ women in Lusaka, and a cohort of 450 HIV+ women in Miami, Florida.
|
| NIH |
HIV Counseling and Testing Among Adolescents in Zambia |
HIV/AIDS |
Prevention |
|
| |
(PI: Julie Denison. 2003) This study will examine the inclusion of family in a voluntary counseling and testing (VCT) program for adolescents.
|
| NIH |
Reduce Postnatal Transmission of HIV Through Breastmilk |
HIV/AIDS |
Prevention |
|
| |
(PI: Donald Thea. 2000-2005.) This study includes a trial of abrupt weaning of infants at the age of four months.
|
| NIH |
Programs in HIV and AIDS Associated Disease/Malignancy |
HIV/AIDS |
Capacity |
|
| |
(PI: Charles Wood. 2000-2005.) To train Zambian health care professionals in the areas of HIV and AIDS associated diseases including malignancies.
|
| NIH |
UAB AIDS/HIV International Training and Research Program |
HIV/AIDS |
Capacity |
Epidemiology,Prevention |
| |
(PI: Sten Vermund. 1998-2004.) University Training Hospital in Lusaka delivers over 4,000 babies each year to HIV+ mothers. This grant supports a...
|
| NIH |
Core -- International Research |
HIV/AIDS |
Capacity |
|
| |
(PI: Susan Allen. 2002) A core grant to support the research capacity of several University of Alabama projects in Zambia.
|
| NIH |
Miami Pediatric AIDS Clinical Trials Unit |
HIV/AIDS |
Capacity |
|
| |
(PI: Gwendolyn Scott. 1988-2007.) The Miami Pediatric Clinical Trials Unit has a research training program for international fellows from Zambia and...
|
| NIH |
Family Planning Promotion to Prevent Unplanned Pregnancies in HIV Infected Zambian Couples |
HIV/AIDS |
General |
General |
| |
(PI: Susan Allen 2002- ) This study will examine the impact of two interventions intended to reduce unplanned pregnancies in couples testing HIV...
|
| Other US |
Maternal TDF and FTC to Reduce NNRTI Resistance Mutations After Intrapartum NVP |
HIV/AIDS |
Drug Development |
|
| |
(Study Director: Benjamin Chi; PI Jeffrey Stringer). This study will examine whether adding tenofovir and emtricitabine to the treatment regimen...
|
| Other US |
Azithromycin Plus Chloroquine Versus Mefloquine for the Treatment of Uncomplicated Malaria in Africa |
Malaria |
Drug Development |
|
| |
(Pfizer Study) This trial will enroll 233 participants in Kenya, Malawi, Uganda, and Zambia in an effort to compare the effects of a treatment...
|
| Other US |
Zambia Integrated Management of Malaria and Pneumonia Study (ZIMMAPS) |
Malaria |
Capacity |
|
| |
Boston University, Center for International Health and Development; and United States Agency for International Development (PI: Kojo...
|
| Other US |
Impact of Different Contraceptives on the Immune System of HIV Infected Women in Zambia (MSRC) |
HIV/AIDS |
General |
|
| |
University of Alabama at Birmingham (PI: Elizabeth Stringer). 66 women testing positive for HIV who want to use contraception will be assigned to...
|
| Other US |
HIV Viral Load Monitoring in Resource-Poor Settings |
HIV/AIDS |
General |
|
| |
University of Alabama at Birmingham, Adult AIDS Clinical Trials Group (PI: Michael S. Saag). 2112 individuals will be enrolled in this clinical...
|
| Other US |
USAID |
HIV/AIDS,Tuberculosis,Malaria |
General |
|
| |
USAID/Zambia is currently implementing a four-year $41 million Zambia Integrated Health Program (ZIHP) in collaboration with the government of...
|
| Other US |
CDC |
HIV/AIDS,Tuberculosis |
General |
|
| |
CDC programs in Zambia include: - TB control, including development of necessary laboratory facilities
- prevention and treatment of
...
|
| International |
A Trial to Evaluate the Safety and Immunogenicity of tgAAC09, an HIV Vaccine Containing Clade C Gag-PR-?RT DNA in an Adeno-Associated Virus (AAV) Capsid, Administered Twice, at Three Dosage Levels and |
HIV/AIDS |
Drug Development |
|
| |
Two Dosing Intervals (TGC 14F). International AIDS Vaccine Initiative and Targeted Genetics Corporation (Study Chair: Eftyhia Vardas; PIs:...
|
| International |
Universal Use of EFV-TDF-FTC and AZT-3TC-LPV/r Combinations for HIV-1 PMTCT in Pregnant and Breastfeeding Women: A Phase 3 Trial (UMA) |
HIV/AIDS |
Drug Development |
Prevention |
| |
French National Agency for Research on AIDS and Viral Hepatitis, Gilead Sciences, Merck, GlaxoSmithKline, Abbott (Study Chairs: Didier K Ekouevi,...
|
| International |
Daily Co-Trimoxazole Prophylaxis to Prevent Malaria in Pregnancy |
HIV/AIDS,Malaria |
Drug Development |
Prevention |
| |
Institute of Tropical Medicine, Belgium and Tropical Diseases Research Centre, Zambia (Study Director: Jean-Pierre Van Geertruyden; PI: Christine...
|
| International |
Mefloquine Prophylaxis in HIV-1 Individuals: a Randomized Placeo-Controlled Trial |
HIV/AIDS,Malaria |
Drug Development |
Prevention |
| |
Institute of Tropical Medicine, Belgium (Study Chair: Umberto D'Alessandro; PI: Modest Mulenga). HIV positive, but asymptomatic, participants...
|
| International |
Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection |
HIV/AIDS |
Drug Development |
|
| |
Indevus Pharmaceuticals, Medical Research Council (United Kingdom), DFID. (PI: Sheena McCormack, MRC; Zambia PIs: Seter Siziya, Maureen...
|
| International |
Controlled Comparison of Two Moxifloxacin Containing Treatment Shortening Regimens in Pulmonary Tuberculosis (REMoxTB) |
Tuberculosis |
Drug Development |
|
| |
University College, London; Medical Research Council; Kilimanjaro Christian Medical Centre, Tanzania; University of Zambia; Medical Research...
|
| International |
Efficacy and Safety of the Pediatric Formulation of Artemether-Lumefantrine in Children with Uncomplicated P. Falciparum Malaria |
Malaria |
Drug Development |
|
| |
Novartis. This trial is designed to determine the safety and effectiveness of a pediatric regimen of artemether-lumefantrine when children ages 12...
|
| International |
Safe and Efficacious Artemisinin-Based Combination Treatments for African Pregnant Women with Malaria (PREGACT) |
Malaria |
Drug Development |
|
| |
Institute of Tropical Medicine, Belgium; Seattle Institute for Biomedical and Clinical Research; National Institute for Medical Research, Tanzania;...
|
| International |
MIM/TDR Grants for Malaria Research |
HIV/AIDS,Malaria |
Epidemiology |
|
| |
A Multilateral Initiative on Malaria (MIM)/TDR Task Force awarded one grant in the amount of $10,000 for malaria research in Zambia in 2002. The...
|
| International |
Phase II Trial to Evaluate the Safety and Efficacy of the Dry Circumcision Method |
HIV/AIDS |
Prevention |
General |
| |
Progressus and University of Versailles (France)(PI: Bertran Auvert). This trial will enroll 15 participants in a study designed to provide...
|
| International |
World Health Organization |
HIV/AIDS,Tuberculosis |
Prevention |
Epidemiology |
| |
WHO provides funds for the following studies in Zambia: - The Prevention of Mother to Child HIV Transmission and ProTEST: A combined
...
|
| International |
Japan |
HIV/AIDS |
Capacity |
|
| |
The Japan International Cooperation Agency (JICA) is supporting the improvement of virology research skills at the University of Zambia Hospital...
|
| International |
Global Fund for AIDS, Tuberculosis and Malaria (GFATM) |
HIV/AIDS,Tuberculosis,Malaria |
General |
|
| |
In Round 1 of funding, the Global Fund approved $42.6 million over two years for Zambian programs addressing HIV/AIDS. Phase 2 of this project was...
|
| International |
Norway (NORAD) |
HIV/AIDS |
General |
|
| |
The Norwegian government's international aid agency (NORAD) is offering financial and technical support to the Zambian government for various health...
|
| International |
DFID (The United Kingdom) |
HIV/AIDS,Tuberculosis |
General |
|
| |
The British Department for International Development (DFID) is actively involved in efforts to mainstream HIV/AIDS issues into other sectors. This...
|
| International |
World Bank |
HIV/AIDS |
General |
|
| |
The World Bank recently approved a $42 million loan to Zambia to combat the AIDS epidemic under the country's national response to HIV/AIDS...
|
| International |
Ireland |
HIV/AIDS |
General |
|
| |
The Irish government, under the Development Co-operation Ireland, will spend the equivalent about $3.44 million US on HIV/AIDS programmes in Zambia...
|
| International |
CIDA (Canada) |
Tuberculosis |
General |
|
| |
In 2002 CIDA committed $11 million in aid to support DOTS programs in high-burden TB countries, including Nigeria, Zambia, Mali and The Gambia in...
|
| NGO |
World Vision International |
HIV/AIDS |
General |
|
| |
World Vision International, a Christian charitable organization, pledged $1 million in 2004 to support HIV/AIDS programs in Zambia.
Source:...
|
| Foundation |
Herpes Simplex Virus Type 2 (HSV-2) Suppression to Prevent HIV Transmission |
HIV/AIDS |
Drug Development |
Prevention |
| |
Gates Foundation (Study Chairs: Connie Celum, Jairam Lingappa, Anna Wald. Zambia PIs: William Kanweka, Susan Allen) This study will enroll 3000...
|
| Foundation |
Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) Antiretroviral Pregnancy Registry A Multi Site Protocol (APR) |
HIV/AIDS |
Drug Development |
General |
| |
Elizabeth Glasser Pediatric AIDS Foundation (Study Director: Lulu Oguda; PIs: Richard Marlink, Joseph Kouakou, Perry Killam). This study will be...
|
| Foundation |
Community-Based Evaluation of a Pilot PMTCT Project in Kafue District |
HIV/AIDS |
Prevention |
|
| |
University of Alabama at Birmingham, Doris Duke Charitable Foundation (PI: Benjamin Chi). In four health clinics in rural Zambia, investigators...
|
| Foundation |
Routine Use of Antiretroviral Therapy to Prevent Mother-to-Child HIV Transmission in the Kafue District of Zambia |
HIV/AIDS |
Prevention |
|
| |
University of Alabama at Birmingham, Doris Duke Charitable Foundation (PI: Benjamin Chi). 320 pregnant, HIV-infected women will be enrolled in...
|
| Foundation |
MTCT-Plus Initiative |
HIV/AIDS |
Prevention |
|
| |
The MTCT-Plus Initiative aims to prevent mother-to-child transmission of HIV in Zambia and other nations with high HIV/AIDS burdens. Chelstone and...
|
| Foundation |
Gates Foundation |
HIV/AIDS |
General |
|
| |
The Bill and Melinda Gates Foundation is supporting various programs in Zambia. In 2000, it made a $750 million contribution to the Global Alliance...
|
| Foundation |
Use of Oraquick for Screening HIV in Children Less than 18 Months Old |
HIV/AIDS |
General |
|
| |
Thrasher Research Fund (PI: Catherine Chunda). This study will test the accuracy of OraQuick to collect and test saliva for HIV infection in...
|